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again, Most synthetic cannabinoids are agonists of the cannabinoid receptors. They are actually built to be similar to THC the purely natural cannabinoid Together with the strongest binding affinity to the CB1 receptor, and that is linked to the psychoactive results or “significant” of cannabis.
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These synthetic analogs usually have higher binding affinity and higher potency towards the CB1 receptors. There are numerous synthetic cannabinoid people categorized according to The bottom construction